Glyphosate inhibits an enzyme that is essential to plant growth; this enzyme is not found in humans or other animals, contributing to the low risk to human health. Comprehensive toxicological studies in animals have demonstrated that glyphosate does not cause cancer, birth defects, DNA damage, nervous system effects, immune system effects, endocrine disruption or reproductive problems. The U.S. Environmental Protection Agency (EPA) classified the carcinogenicity potential of glyphosate as Category E: “evidence of non-carcinogenicity for humans.”
EPA, which reviews extensive toxicological and environmental data before registering an active ingredient, classifies glyphosate as “practically non-toxic.” That is the most favorable acute toxicity category possible based on single–exposure oral, dermal and inhalation studies. In addition to studies with the active ingredient of herbicide products, regulatory agencies also require specific toxicological studies with the full formulation.